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Carcinogenesis, Mutagenesis, and Impairment of Fertility: No long-term studies in animals have been performed to evaluate the carcinogenic potential of ABELCET � . The following in vitro (with and without metabolic activation) and in vivo studies to assess ABELCET � for mutagenic potential were conducted: bacterial reverse mutation assay, mouse lymphoma forward mutation assay, chromosomal aberration assay in CHO cells, and in vivo mouse micronucleus assay. ABELCET � was found to be without mutagenic effects in all assay systems. Studies demonstrated that ABELCET � had no impact on fertilit..